HI Point Carbine in .45 ACP for hunting Deer?

ok i got a friend that wants to know if it would be legal or humane to hunt whitetail deer in Virginia using a HI Point Carbine in .45 cal with a 230gr bullet, distance is going to be no more then 100 yards or less when shooting cause of mountian areas, i opted to say no but still the question lingers so please blast away with answers thanks guys.